On the evening of Nov. 7, Steffanie Strathdee sent out a cryptic tweet: “#Phage researchers! I am working with a team to get Burkholderia cepacia phages to treat a 25 y old woman with CF whose infection has failed all #antibiotics. We need lytic non-lysogenic phage URGENTLY to find suitable phage matches. Email if you can help!” The message was retweeted nearly 400 times.
Viruses discovered a century ago may be our best defense against a threat that could kill 10 million people a year by 2050
Antibiotic resistance — the phenomenon in which bacteria stop responding to certain antibiotics — is a growing threat around the world.
It’s expected to kill 10 million people annually by 2050.
Na klimaatverandering en massale insectensterfte bestaat nog een groot gevaar voor de wereld waarin wij leven: resistente bacteriën. Door massaal gebruik van antibiotica zijn steeds meer bacteriën juist opgewassen tegen die antibiotica. Oplossing: een bacteriofaag, kortweg faag. Een klein virus dat alleen een specifieke bacterie infecteert. Antoinette Hertsenberg maakte er een uitzending over in het kader van het programma ‘Dokters van morgen’.
As overused antibiotics become less and less effective, a tantalising discovery may revolutionise healthcare
- Steffanie Strathdee feared the worst when husband Tom Patterson comatosed
- Husband of 13 years lay in a deep coma, the victim of an aggressive superbug
- His heart, lungs and major organs were all shutting down with little hope left
- Apparently miraculous recovery is result of natural phenomenon that could combat growth of antibiotic-resistant infections and also treat sore throats
International research involving a Monash biologist shows that bacteriophage therapy – a process whereby bacterial viruses attack and destroy specific strains of bacteria – can be used successfully to treat systemic, multidrug resistant bacterial infections.
Writing in the September issue of the journal Antimicrobial Agents and Chemotherapy, a large and diverse team of researchers has published the full details of the dramatic, experimental and ultimately successful effort to save the life of a patient infected with a multidrug-resistant bacterium. The findings describe a potentially powerful new tool — bacteriophages https://en.wikipedia.org/wiki/Bacteriophage — for addressing the global spread of microbial pathogens impervious to current antibiotic treatments and standards of care.
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For every 100 hospitalised pediatric patients across India who may need a common antibiotic called ampicillin to fight infections, chances are it won’t help 95 of them. In 75% of hospitalised children, especially those younger than one month old, another common antibiotic, gentamycin, may not work.
The reason, according a recent study by pediatricians of Apollo Hospital in Navi Mumbai, is that antibiotic resistance has risen to alarming levels among India’s youngest.