Eliava Phage Therapy Center
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Superbugs: A Rising Threat To Society & What We Can Do About Them

“It is not difficult to make microbes resistant to penicillin in the laboratory by exposing them to concentrations not sufficient to kill them … The time may come when penicillin can be bought by anyone in the shops. Then there is the danger that the ignorant man may easily underdose himself and by exposing his microbes to non-lethal quantities of the drug make them resistant.” – Alexander Fleming, Nobel lecture, 1945.

 

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Viruses cure cholera

Phage therapy may finally be gaining ground in the United States. Researchers from Tufts University just reported that a virus cocktail effectively prevents cholera in an animal model.

According to study author Andrew Camilli, “while phage therapy has existed for decades, our study is proof-of-principle that it can be used to protect against infection and intervene in the transmission of disease. We are hopeful that phages can someday be a tool in the public health arsenal that helps decrease the global burden of cholera, which affects up to four million people around the world each year.”

 

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A Woman Was Killed by a Superbug Resistant to All 26 American Antibiotics

Yesterday morning, I published a story about the silent spread of resistance against the antibiotic of last resort, colistin—a major step toward the emergence of a superbug resistant to all antibiotics. While reporting this story, I interviewed Alex Kallen, an epidemiologist at the CDC, and I asked if anyone had found such a superbug yet. “Funny you should ask,” he said.
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A virus, fished out of a lake, may have saved a man’s life — and advanced science

Dodge Pond, which sits on the outskirts of East Lyme, Conn., is an ordinary New England lake. It’s home to fish like bluegill and alewife, along with smaller organisms like water fleas, algae, and bacteria. There are viruses in Dodge Pond, too, most of which infect its bacteria. And one of Dodge Pond’s viruses, known as OMKO1, has now earned it a place in medical history.

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Antibiotics crisis: is phage therapy the answer?

It’s been used in the former USSR for a century. Now the West is taking notice

 Bacteriophage – or ‘phage’ for short – is a virus that infects bacteria. These naturally occurring infective agents contaminate bacterium and replicate once within. They are everywhere – including all over our bodies where they outnumber bacteria 10 to one – and are one of the most common entities in the biosphere.

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